Index

C

computed identifier

D

digest, ga4gh_digest

H

How can I learn more about VRS? How can I get involved? How do you communicate the uncertainty about variants meaningfully to other providers? How do you deal with variation that need to hold large amounts of data?

How do you handle variant representations and annotation across multiple transcripts and reference builds? How do you represent different types of variation in a unified way (e.g. gene fusions)? How do you represent genotypes, especially for mosaicism and somatic variants (multi-ploidy)? What existing tools can help bridge single-location variants and genotypes with VRS? How does VRS handle strandedness?

I

identifiable object

S

serialization

W

What makes it special/different/better than SPDI, VCF, and others?

Why does VRS ...? Why did you use interresidue coordinates? Are they they same as 0-based coordinates? Why aren't sequences typed?